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Dr. Paul W.K. Rothemund and Dr. Eric Winfree awarded the Feynman Prize at nanoTX Conference

Dr. Paul W.K. Rothemund and Dr. Eric Winfree were awarded the 2006 Foresight Institute Feynman Prizes at the nanoTX Conference last week, at a special awards reception. (I earlier blogged about H. Ross Perot’s keynote address at this conference.)

Rothemund was on-hand to receive the award, and I was fortunate to be able to attend his presentation on his and Winfree’s research. Rothemund delivered first a presentation on his work, and then he delivered a presentation on behalf of Winfree who could not attend.

Rothemund’s work is fantastic — he works upon Algorithmic Self-Assembly. He’s been able to program long strands of viral DNA such than when mixed in a suspension with other short DNA snippets (and heated slightly), the snippets or “staples” will bind to the long strand in particular order, causing it to fold back upon itself to form precise shapes. Rothemund has nicknamed what he does as “DNA Origami”, although the key concept is the ability to program the DNA to order itself into near two-dimensional, or even three-dimensional shapes. As proof of concept, Rothemund has programmed DNA to fold itself into words, stars, smiley faces, and other shapes.

DNA Smiley
Smiley composed of one long DNA strand
The staple snippets of DNA are not shown in this representation.
(Illustration copyright 2006 by Chris Silver Smith.)

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